Synthesis of Monovitamin E Succinate and its Application in Cigarettes

Abstract

In order to increase the delivery of vitamin E(VE) in mainstream cigarette smoke and improve smoking taste,monovitamin E succinate was synthesized from VE and succinic anhydride,the synthetic was analyzed by HPLC,and identified by 1H NMR,13C NMR and EI-MS.The smoke analysis and sensory evaluation of the cigarettes spiked with the synthetic were carried out.The results showed that: 1) The synthetic was the target product,monovitamin E succinate,with the purity of 98%.2) The delivery of VE increased in mainstream smoke of the cigarette spiked with monovitamin E succinate.3) The smoke irritation of the cigarette containing monovitamin E succinate decreased,and smoking taste improved.monovitamin E succinate has the functions of increasing VE delivery in mainstream cigarette smoke,reducing smoke irritation,and improving cigarette smoking taste.