Abstract

AbstractTri‐3,4‐dimethoxycinnamoyl‐1,5‐γ‐quinide was synthesized and fully characterized by a direct synthesis from quinic acid and a large excess of 3,4‐dimethoxycinnamoyl chloride. Mono‐ and di‐3,4‐dimethoxycinnamoyl‐1,5‐γ‐quinides were also obtained from the direct coupling of 1,5‐γ‐quinide and 3,4‐dimethoxycinnamoyl chloride in different molar ratios. Moreover, a hypothetical mechanism of the direct lactonization is proposed.

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