Abstract
Background:2,4,6-Trichlorophenol (2,4,6-TCP) is one of the most significant pollutants among chlorophenols due to its harmful effects. It has been classified as priority pollutants by the U.S. Environmental Protection Agency. Therefore, highly selective separation and sensitive recognition of 2,4,6-TCP from complex samples are in great demand.Methods:For this purpose , the preparation of MIPs selective for 2,4,6-TCP was carried out by precipitation polymerization. A non-covalent approach was employed to establish an interaction between template and monomer (methacrylic acid).Results:The resulted polymers were characterized by scanning electron microscopy (SEM), EDX, Fourier-transform infrared spectroscopy(FT-IR) and BET. The batch binding assay was carried out to select the most selective polymer in terms of binding efficiency towards the target template. The adsorption parameters such as initial concentration, dosage of polymer, pH effect and selectivity with structural analogues were determined . The selectivity of MIP towards the 2, 4, 6-TCP was higher as compared to its structural analogue melamine with a good adsorption efficiency. Furthermore, the MIP as an extracting material was applied for extraction of 2, 4, 6-trichlorophenol from the spiked blood serum (88%) and river water sample (94%). The results showed that the optimized MIP could successfully extract 2,4,6-TCP from the blood serum and river water.Conclusion:The molecularly imprinted polymers for 2,4,6-TCP have been prepared by precipitation polymerization with a non-covalent approach. The optimized MIP has been successfully used for the extraction of 2,4,6-TCP from blood serum and river water.
Highlights
ResultsThe resulted polymers were characterized by scanning electron microscopy (SEM), energy dispersive X-rays (EDX), Fourier-transform infrared spectroscopy(FT-IR) and BET
Chlorophenols (CPs) are considered as uncontrolled environmental pollutants due to their toxicity, carcinogenicity, and bioaccumulation capability [1]
Carcinogenic properties, and persistence in the environment have led to an idea to synthesize Molecularly imprinted polymers (MIPs) for removal of 2,4,6-TCP from human blood serum and environmental water to protect from its hazardous effects
Summary
The resulted polymers were characterized by scanning electron microscopy (SEM), EDX, Fourier-transform infrared spectroscopy(FT-IR) and BET. The batch binding assay was carried out to select the most selective polymer in terms of binding efficiency towards the target template. The adsorption parameters such as initial concentration, dosage of polymer, pH effect and selectivity with structural analogues were determined. The selectivity of MIP towards the 2, 4, 6-TCP was higher as compared to its structural analogue melamine with a good adsorption efficiency. The MIP as an extracting material was applied for extraction of 2, 4, 6-trichlorophenol from the spiked blood serum (88%) and river water sample (94%). The results showed that the optimized MIP could successfully extract 2,4,6-TCP from the blood serum and river water
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have