Abstract
Methyl α-isomaltoside and methyl α-isomaltotrioside analogues specifically deoxygenated at position C-2 of various glucopyranosyl units were synthesized by condensation of either 6-O- acetyl-3-O- benzoyl-4-O- benzyl-1-O-tert- butyldimethylsilyl-2-deoxy-β- d-arabino- hexopyranose (trimethylsilyl triflate mediated) or 6-O- acetyl-2,3,4-tri-O- benzyl-α- d-glucopyranosyl chloride (mediated by silver carbonate and silver triflate) with suitably blocked derivatives of methyl α- d-glucopyranoside, its 2-deoxy analogue, or methyl 2′-deoxy-α-isomaltoside.
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