Abstract
Abstract Methyl 2-acetamido-2-deoxy-5,6-O-isopropylidene-β-D-galactofuranoside was prepared in one step from 2-acetamido-2-deoxy-D-galactose and 2,2-dimeth-oxypropane in good yield. Condensation of this compound with acetobromo-galactose using mercury (II) cyanide as catalyst followed by removal of the protecting groups from the resulting disaccharide derivative yielded the Thomsen-Friedenreich (TF) antigenic disaccharide.
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