Abstract
Alkylation of ethyl isocyanoacetate with 1,2-bis(4-bromomethylphenyl)ethane under phase transfer catalysis (PTC) as well as phosphazene base (2-tert-butylimino-2-diethylamino-1,3- dimethylperhydro-1,3,2-diazaphosphorine (BEMP)) conditions gave the macrocyclic cyclophane based unusual α-amino acid derivatives.
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