Abstract
A copper-catalyzed aerobic oxidative coupling of aryl methyl ketones with <i>N</i>,<i>N</i>-dimethylformamide was developed, which afforded α-ketoamides by a sequence of dioxygen activation, C–H bond functionalization, and amide formation with <i>N</i>,<i>N</i>-dimethylformamide as the nitrogen source. Molecular oxygen was found to play a crucial role in this transformation.
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