Abstract
Fabrication processing of a intermediate, 2,4,5-trimethoxy-α-chlor-acetophenone, was reported in details in this paper. The intermediate is the key substance for synthesis of lamellarin H and its derivatives by a simple synthesis route proposed recently. Lamellarin H has been shown to have antitumour activity (in particular, against human lung cancer) and anti-HIV properties. The formed intermediate was identified by means of IR spectrum, HPLC, UV spectrum, H NMR and melting point measurement.
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