Abstract
A new synthesis of indolizine derivatives was developed by utilizing the [1,2]-phospha-Brook rearrangement under Bronsted base catalysis. The method involves the generation of allenylpyridine from alkynyl 2-pyridyl ketones through the [1,2]-phospha-Brook rearrangement and the following cycloisomerization without using transition-metal catalysts. The method can be performed in a one-pot fashion and directly provides indolizine derivatives having a phosphate moiety that can function as a handle for further manipulation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
