Abstract
Abstract Domino reactions have received great attentions of organic chemist as an efficient protocol to synthesize indole derivatives. In this process, it is not required isolating or purifying the intermediates, changing the reaction condition and adding reagents. Transition metal-catalyzed domino reactions to synthesize indole derivatives have already been widely studied and become a powerful tool. In this paper, the progress of recent domino reactions applied to construct indole and its derivatives is reviewed, focusing on the transition metal-catalyzed domino reactions, and detailed analysis on the versatility and applications.
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