Synthesis of hydroxyethyl starch derivatives with phenylpropanoid fragments attached through ester or sulfide bonds

Abstract

Approaches to the synthesis of hydroxyethyl starch derivatives containing phenylpropanoic acid fragments with various degree of substitution were suggested. Esterification of hydroxyethyl starch in heterogeneous aqueous organic medium gave rise to the corresponding esters of ferulic, p-coumaric, and sinapinic acids. A reaction of hydroxyethyl starch mercaptodeoxy derivative with acetoxy derivatives of these hydroxycinnamic acids led to the mixed polysaccharides with the oxyphenyl-3-mercaptopropanoic acid fragments.