Abstract
A facile, diastereoselective method for the synthesis of diaziridines with C- and N-cyclopropyl substituents has been developed, N-cyclopropyldiaziridines being for the first time synthesized. The method is based on one-pot three-component condensation of cyclopropyl-containing carbonyl compounds, primary aliphatic amines including cyclopropylamine, and N-chloroalkylamines in organic solvents in the presence of bases under mild conditions.
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