Synthesis of high luminescent Eu3+ doped nanoparticle and its application as highly sensitive and selective detection of Fe3+ in real water and human blood serum

Abstract

The present work reports a highly efficient Ca doped Eu: Y2O3 i.e Ca0.05Eu0.01Y1.94O3 (CEY.) nanophosphor material synthesized through a facile combustion method, as a simple and selective turn-off fluorescence probe for the quantitative analysis of iron ions (Fe3+). The proposed sensor allows the quantification of iron in the range of 10 µM–90 µM with a limit of detection (LOD) ∼ 63.2 nM under the natural pH range. Moreover, CEY nanophosphor shows an excellent fluorescence phenomenon with a gradual increase in the Fe3+ ion concentration. It has been observed that the corresponding PL intensity gets completely quenched with 500 µM Fe3+ ion concentration. Furthermore, the applicability of the sensor as an efficient probe has been investigated with real water samples, iron tablets, and human blood serum (HBS). The selectivity of the probe has also been analyzed with various metal ions and biomolecules. Thus, in turn, the as-obtained sensing probe illustrates an excellent accuracy, sensitivity, and selectivity, and offers potential application in clinical diagnosis, biological and real water sample studies, with the detection of Fe3+ ion. Furthermore, it does not require any acidic medium for a level-free, and non-enzymic detection of a real sample with almost not affecting the sample quality and henceforth provides more reliable results.