Abstract
Incorporation of ( 35S)-sulfate into glycosaminoglycans (GAG) of toadfish islets of Langerhans in vitro was examined. ( 35S)-sulfated GAG were synthesized by a component of the microsomal fraction, and subsequently transferred to the secretion granules, mitochondria and nuclei. The predominant type of GAG synthesized was heparan sulfate, but chondroitin 4-and 6-sulfate and dermatan sulfate were also found.
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