Abstract
Gangliosides, glycosphingolipids containing sialic acid(s) in the glycan moieties, as major constituents of functional membrane domains such as lipid rafts participate in various biological processes. Previously, we developed fluorescent ganglioside analogs useful for single-molecule imaging of lipid raft formations. In this paper, we describe the development of a, 6-N3-GalNTCAc donor and its application to the synthesis of fluorescent gangliosides containing fluorescent GalNAc residue(s) at the glycan terminus, namely, fluorescent analogs of GalNAc-GD1a and asialo-GM2.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
