Abstract

The efficient synthesis of fully substituted pyrazoles with a dicyanomethyl group was developed via an annulation reaction of 2-aroyl D-A cyclopropanes with arylhydrazines in the presence of DBU/AlCl3 reaction systems. This synthetic approach featured a wide range of readily available aroyl-substituted D-A cyclopropanes with diverse functional groups and a diversity of substituents on pyrazole products and had operationally simple and mild reaction conditions.

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