Abstract
Fluorescein isothiocyanate(FITC)-labeled vancomycin(FITC-Vanco,FV) was synthesized.After purified by preparative HPLC,the structure of the target compound was indentified by MS.Its combination amount toward bacteria with different concentration was evaluated by the fluorescence intensity of the bacterial suspension.FV synthesized in this study shows specific binding with different bacteria.It shows promising application value in studying bacterial resistance mechanism and bacterial susceptibility to vancomycin.
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