Abstract

Hydrolytically-resistant pseudodisaccharides incorporating an azafuranose have been prepared by coupling 6-amino-2,5-imino- d-glucitol derivatives with d-glucose, either through an ester or an amide bond. Synthesis of the azasugar templates was achieved by nucleophilic opening of a C 2 symmetric bis-aziridine deriving from d-mannitol.

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