Abstract
AbstractThe 5‐endo iodine‐promoted ring closure of 4‐allyl‐4‐(alkylamino)cyclohexanone derivatives gives the corresponding 1‐azaspiro[4.5]decanes in good yields. The reaction was tested with enantiopure homoallylamines to evaluate the diastereoselectivity of the process and to provide a route for possible intermediates to the natural products embodying this azabicyclic ring.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
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