Synthesis of Dimethyl Octahydroquinazolinones by using Electrochemically Prepared Copper Oxide Nanoparticles

Abstract

Present work involves the synthesis of substituted dimethyl octahydroquinazolinones by using electrochemically prepared copper oxide nanoparticles as catalyst in microwave. Copper oxide nanoparticles were prepared in appreciable yield by using electrochemical reduction method of synthesis in the presence of tetrabutylphosphonium bromide for capping. The prepared nanoparticles were analyzed by UV, FTIR, TGA, X-ray diffraction and electron microscopic studies. The nanoparticles of copper oxide then were successfully used as a catalyst in multicomponent reaction between diketones, substituted aldehydes and urea/thiourea to synthesize substituted dimethyl octahydroquinazolinones.