Abstract
Reported is a base-promoted tandem ring opening of N-substituted aziridines with propargylic alcohols followed by ring closing onto the tethered alkyne to give dihydroxazines in moderate to good yields. Selected examples of dihydroxazines were further reduced to 3,5-disubstituted morpholine derivatives with poor to high (where cis isomer predominates) diastereoselectivity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
