Abstract
Directed ortho-metalation (DoM) strategy has been applied for the development of a short procedure for the regiospecific synthesis of [phenyl-2H4]-2-bromo-benzylamine 6 starting from commercially available [phenyl-2H5]-benzoyl chloride 1. A strong isotope effect was observed during the ortho-substitution. Copyright © 2005 John Wiley & Sons, Ltd.
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More From: Journal of Labelled Compounds and Radiopharmaceuticals
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