Synthesis of deuterium and tritium labelled phenyl glycine

Abstract

A new method of synthesis of phenyl glycine labelled with deuterium and tritium was elaborated. Labelled phenyl glycine was obtained by isotope exchange method between phenyl glycine and deuterated or tritiated water at elevated temperature in hydrochloric acid medium using K2PtCl4 as a catalyst. 37 GBq /1 Ci/ HTO was used for the synthesis of tritiated phenyl glycine and labelled product with specific activity of 185 MBq/mole /5 mCi/mole/ was obtained.