Synthesis of Dendrimers: Convergent and Divergent Approaches

Abstract

Dendrimers can be prepared by both convergent and divergent approaches. In the convergent approach, first suitable building blocks are prepared and then connected by lego chemistry, ligations or click chemistry. In the divergent approach, the synthesis is done stepwise. The advantage of convergent synthesis is greater difference between product and side products. The purification is therefore easier. On the other hand, the synthesis of big building blocks is complicated.