Synthesis of cyclic saturated sulfones by the catalytic reduction of unsaturated compounds

Abstract

The synthesis of sulfones of thiacyclohexanes, thiadecalins, and perhydrothioxanthenes by the catalytic hydrogenation of the corresponding α,β-unsaturated cyclic sulfones in the presence of palladium on carbon was developed. The effects of the temperature conditions, excess hydrogen pressure, the nature of the grouping in the 4 position of the heteroring, and the degree of shielding of the double bond on the process were established.