Synthesis of Core-Shell Nanoparticles (Cu:Se) by Plasma Jet for Parasitic Leishmaniasis Treatment

Abstract

Cu:Se core-shell nanomaterials were created using atmospheric cold plasma in order to treat parasite leishmaniasis. In this investigation, leishmania parasite treatment was examined experimentally (<i>Leishmania tropica</i>). Specifically, a 1mm diameter high-voltage electrode was used to produce atmospheric pressure non-thermal plasma. Cu:Se nanoparticles (NPs) were made using copper and selenium salts in aqueous solution as a precursor. The NPs were examined using X-ray diffraction, ultraviolet spectroscopy, and field emission scanning electron microscopy (FESEM). The ideal concentration (3:7) yields grains with a diameter of 17 nm. Morphology of the Cu:Se NPs was studied with FESEM. Observations show that the synthesized NPs were spherical (cluster) in shape with diameters of 15-50 nm, the samller size the samller size of NPs was the best for treatment of NPs was the best for treatment of parasitic leishmaniasis were created. After 48 h of exposure, the percentage of <i>L. tropica</i> parasites for the parasites at a molar concentration of 3:7, 30 min of Cu salt exposure, and 10 min of Se salt exposure, was equal to 78.8%. The core-shell NPs are a viable method for treating the parasite leishmaniasis that threatens people all over the world, according to the results.