Abstract
Development of green technology is generating interest of researchers towards ecofriendly and low-cost methods for biosynthesis of nanoparticles (NPs). In this study, copper oxide (CuO) NPs were synthesized using a copper nitrate trihydrate precursor and Catha edulis leaves extract as a reducing and capping agent during the synthesis. The biosynthesized CuO NPs were characterized using an X-ray diffractometer (XRD), scanning electron microscopy-energy-dispersive X-ray spectroscopy (SEM-EDS), transmission electron microscope (TEM), Ultraviolet visible spectroscopy (UV-Vis), and Fourier transform infrared (FTIR) spectroscopy. XRD characterization confirmed that the biosynthesized CuO NPs possessed a good crystalline nature which perfectly matched the monoclinic structure of bulk CuO. Furthermore, the results obtained from SEM and TEM showed that the biosynthesized CuO NPs were spherical in shape. EDS characterization of the biosynthesized NPs also indicated that the reaction product was composed of highly pure CuO NPs. Moreover, the antimicrobial activities of different concentrations of CuO NPs synthesized using Catha edulis extract were also tested. Accordingly, the result showed that the highest zone of inhibitions measured were for CuO NPs synthesized using 1 : 2 ratios at 40 mg/ml solution concentration and observed to be 22 ± 0.01 mm, 24 ± 0.02 mm, 32 ± 0.02 mm, and 29 ± 0.03 mm for S. aureus, S. pyogenes, E. coli, and K. pneumonia, respectively.
Highlights
Worku Wubet Andualem,1 Fedlu Kedir Sabir,2 Endale Tsegaye Mohammed,3 Hadgu Hailekiros Belay,2 and Bedasa Abdisa Gonfa 2
Studies have indicated that biomolecules such as proteins, phenols, and flavonoids play a role in reducing the ions to nanosize and play an important role in the capping of NPs [32]. erefore, this work aimed to explore the application of Catha edulis leaves extract as a capping and reducing agent for the synthesis of CuO NPs in addition to its consumption as amphetamine-like psychostimulant drug worldwide and evaluate the antibacterial activities of the synthesized CuO NPs against selected pathogenic organisms using the agar disc diffusion method
3.1. ermal Gravimetric Analysis (TGA). e as-synthesized CuO NPs using copper nitrate trihydrate precursor salt and Catha edulis leaves extract were characterized by using TGA/DTA. e weight losses of the investigated materials were analyzed
Summary
Worku Wubet Andualem, Fedlu Kedir Sabir, Endale Tsegaye Mohammed, Hadgu Hailekiros Belay, and Bedasa Abdisa Gonfa 2. CuO NPs can be synthesized using various physical and chemical methods such as electrochemical reduction [8, 9], sonochemical methods [10,11,12], chemical precipitation [8], solution plasma, thermal decomposition [11], microwave irradiation [13], and the sol-gel method [14,15,16]. Even though these synthesis methods of NPs are easy and provide high yields, the use of toxic chemicals as reducing agents remains a major concern. Journal of Nanotechnology the toxicity of the NPs. erefore, utilizing biological sources for the synthesis of NPs could provide a favorable, nontoxic, and ecofriendly approach [17]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
