Abstract

In the presence of an equimolar amount of Lewis acid such as magnesium bromide and ytterbium trifluoromethanesulfonate, 1,3-dipolar cycloaddition reactions of aromatic nitrile oxides to a chiral 3-acryloyl-2-oxazolidinone gave the corresponding chiral 2-isoxazolines in a diastereoselective manner.

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