Synthesis of chiral cyclodextrin metal‐organic framework modified with platinum on glassy carbon electrodes: Electrochemical chiral recognition of methionine enantiomers

Abstract

AbstractA platinum nanoparticle‐modified chiral cross‐linked cyclodextrin MOF (Pt‐CLMOF) was synthesized. Then, a chiral electrochemical sensor was constructed using the Pt‐CLMOF nanomaterials for the recognition of methionine (Met) enantiomers and the chiral recognition mechanism was revealed by density functional theory calculations. The recognition effect of Pt‐CLMOF modified electrode (Pt‐CLMOF/GCE) on Met was studied by differential pulse voltammetry. The enantioselectivity coefficient (IL/ID) was 1.98. There is an acceptable linear relationship between peak current and Met enantiomer concentration in the 2–200 μM range, the detection limits of L–Met and D‐Met were 0.33 and 0.60 μM which were obtained by this electrochemical sensor, respectively. The synthesized materials were successfully applied to the analysis of Met enantiomers, indicating that Pt‐CLMOF materials have good application potentiality.