Synthesis of Certain 3‐Aminopyrazolo[5,4‐b]pyridine and 3,4‐Substituted Pyrido[2′,3′ :3,4]pyrazolo[5,1‐c][1,2,4]triazine Derivatives

Abstract

Abstract2‐Thioxo‐1,2‐dihydropyridine derivatives 2a, 2b were reacted with methyl iodide to give 2‐methylthiopyridines 3a, 3b, which were reacted with hydrazine hydrate to produce 3‐aminopyrazolo[5,4‐b]pyridines 4a, 4b. Compounds 4a, 4b were diazotized to afford the corresponding diazonium salts 5a, 5b, which were reacted with some active methylene compounds 6a–6h to give the corresponding pyrido[2′,3′:3,4]pyrazole[5,1‐c][1,2,4]triazines 7–14.