Synthesis of cellulose aerogels as promising carriers for drug delivery: a review

Abstract

Cellulose is an important raw material used for the preparation of aerogel materials in life sciences. Cellulose aerogel's excellent biocompatibility, biodegradability, and nontoxicity combined with its multiple chemical functions make it an ideal carrier for drug delivery. Cellulose aerogels offer high porosity, large specific surface area, and ultra-light density. They can be used as drug carriers to improve bioavailability and drug loading. We reviewed the methods used to prepare cellulose aerogels with nanocellulose, renewable cellulose, and cellulose derivatives as raw materials. In addition, we described cellulose aerogels as a drug delivery carrier to inspire work in new drug delivery systems that intelligently use cellulose aerogels. Finally, we described the application prospects of intelligent and responsive cellulose aerogels in drug delivery systems.