Abstract
AbstractAn efficient and practical method for the synthesis of carboxylic acids, esters, and amides from 1,1‐dibromoalkenes has been developed. The reactions proceed through a key process, the C(sp)−B bond oxidation of alkynyl boronate intermediates with Oxone. This protocol features broad substrate scope, good efficiency, and good functional group compatibility. Moreover, the synthetic practicability was demonstrated by easy gram‐scale preparation and the synthesis of drug molecules.
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