Abstract
We have reported on the synthesis of carbazoles by inter- and intramolecular Michael addition. 1 Ellipticine derivatives are related to these compounds, and especially those with 9-methoxy- and 9-hydroxy substituents exhibit appreciable antitumor and antileukemic activity. 2 Therefore, we have prepared the tetrahydrocarbazoles 7a and 7b, starting from N-benzyl-2-formyl-5-methoxyindole ( 2a) and N-benzyl-2-formyl-7-methoxyindole ( 2b), respectively.
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