Abstract

Alkyl thioimidates react with hydrazides of methyl hydrogen oxalate and oxamic acid to yield methyl 1,2,4-triazole 3(5)-carboxylates and -carboxamides. Ribo-, deoxyribo- and arabino-C-nucleoside analogues of ribavirin have been prepared and their structures established by n.m.r. and mass spectrometry.

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