Abstract

An efficient method has been developed for the synthesis of bis-exocyclic conjugated diene containing 1,2,3,4-tetrahydroquinoline derivatives via palladium-catalyzed intramolecular Heck cyclization of (2-bromo-allyl)-(2-phenylethynyl-phenyl)-amines. The reaction followed 6-exo-dig cyclization to yield the desired products in moderate to good yields.

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