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Abstract
The syntheses are described of four isosteric racemic myo-inositol 1,4,5-trisphosphate ( 1) analogues with the phosphate groups replaced by sulfonamide ( 2), sulfate ( 3), methylphosphonate ( 4), and carboxymethyl ( 5). None of these compounds had any affinity for the IP 3 receptor or induced platelet aggregation.
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