Abstract
An amphiphilic dendrimer (DPEA-PEG) grafting polyethylene glycol at the terminals was prepared by endcapping of dendritic poly(ether-amide) (DPEA) with isocyanate terminated linear polyethylene glycol (PEG-NCO). The molecular structure was verified by gel permeation chromatography (GPC), 1H NMR and FT-IR. The micelle characteristic of DPEA-PEG in water was investigated. The critical micelle concentration (CMC) was determined by a fluorescence technique to be 55.5mg/L. The hydrodynamic radius of micelles was measured by dynamic light scattering (DLS) to be 76.2nm. The UV–vis spectrum showed that the solubility of salicylic acid increased from 1.91 to 2.78mg/L when the concentration of DPEA-PEG attained 5mg/mL in an aqueous solution.
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