Abstract

An approach to the synthesis of amphiphilic glycophospholipids based on β-cyclodextrin (β-CD) was proposed. Distinctive features of the proposed method are the use of highly efficient trivalent phosphorus derivatives in the first steps of the synthesis and the regioselective monophosphorylation of nonprotected β-CD. The efficiency of using 13С NMR spectroscopy for the determination of the position and number of phospholipid residues introduced into the CD composition was shown.

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