Abstract
This study involves the aromatization reactions of some ketone derivatives through Manganese (III) acetate. The ketone derivatives used in the study are α-tetralone (1a), 2,4,7-trimethyl-7,8-dihydro quinolinone (1b). At the end of the aromatization reactions of these ketone derivatives the synthesized structures of α-naphthol (2a), 2,4,7-trimethylquinoline-5-ol (2b) were identified by spectroscopic methods such as IR, 1H-NMR, 13C-NMR, FAB-MS respectively. Micro-organism types such as Escherichia coli, ATCC 25922, Klepsiella pneumoniae, Staphylococcus aureus NRRL B767, Salmonella typhimurium NRRLB 4420, Bacillus subtilis NRS 744, Bacillus cereus ATCC 11778, Micrococcus luteus ATCC-9341, Listeria monoaytopenus ATCC-7644 bacteria and yeast fungus Candida albicans were used to study the anti-microbial properties of the synthesized 2b compound. The obtained results have determined that compound number 2b has a good antibacterial impact on Bacillus subtilis (NRS-744).
Highlights
Major developments have taken place in the area of reactions with free radicals during recent years in parallel with the developments in technology and laboratory tools and equipment
The initial studies carried out with Manganese (III) acetate involved the generation of lactone and dilactone from alkenes, the oxidation of substituted aromatic compounds and addition reactions
At the end of this process the reaction mixture is put into an evaporator to remove the benzene. 2,4,7-trimethyl-7,8-dihydro quinolinone (1 mmol; 0.189 g) is added onto the Manganese (III) acetate remaining in the reaction flask and the flask is fitted with the condenser and boiled
Summary
Major developments have taken place in the area of reactions with free radicals during recent years in parallel with the developments in technology and laboratory tools and equipment. The present usage area of free radicals has expanded rather comprehensively. The main usage areas are organic chemistry, polymer chemistry and the chemistry of complex natural products. The similarity in reactivity in spite of the fundamental differences in the structures of these metal complexes is noteworthy These results show that the mechanism and method of the realized reactions are the same. The initial studies carried out with Manganese (III) acetate involved the generation of lactone and dilactone from alkenes, the oxidation of substituted aromatic compounds and addition reactions. In subsequent years the radical cyclization reactions between Mn (III) and the alkenes of 1,3-dioxo compounds (malonic ester, acetylacetone, etc.) have been studied in detail. The addition-cyclization reactions of enolizable 1,3-dicarbonile compounds through Manganese (III) acetate have been studied [14]-[20]. The biological activity properties of the synthesized compounds were tested
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
