Synthesis of amino acid-containing polyacids and their application in self-cured glass-ionomer cement

Abstract

Six methacrylate or acrylate derivatives of natural amino acids were synthesized and characterized. Based upon these monomers, six terpolymers [poly(acrylic) acid-co-itaconic acid-co-amino acid] were prepared and characterized. The synthesized polymers were used to formulate glass-ionomer cements (GICs) using Fuji II glass filler. The effects of the molecular weight (MW) and powder/liquid ( P/ L) ratio were evaluated. Scanning electron microscopy (SEM) was used to examine the fracture surfaces of the selected cement specimens. Results show that all the amino acid modified GICs exhibited higher compressive strengths (CS, 193–236 MPa) and much higher flexural strengths (FS, 55–71 MPa) as compared to commercial Fuji II GIC (191 in CS and 16 in FS). Both MW and P/ L ratio affected the strength of the formed cement. It was important to find the optimal MW and P/ L ratio to obtain the highest FS. In this study, optimized MW (number average) of the polyacids and P/ L ratio were around 50,000 and 2.7/1, respectively. The microstructures of the fracture surfaces helped to explain the strength differences among the materials tested in the study. SEM analysis suggests that more integrated microstructures and fewer defects can lead to higher FS.