Abstract
Successful synthesis of amino acid and aniline derivatives of 6,7-dibromo-5,8-quinolinedione is reported. 6,7-Dibromo-5,8-quinolinedione was prepared by nitrosation of 8-hydroxyquinoline, followed by subsequent amination and oxidation of the resulting intermediates. Thereafter, addition of amino acids and anilines supplied the desired products. Effect of solvent on reaction yield and time showed pyridine as the best amongst the studied solvents. Structural elucidation was done using proton NMR and mass spec.
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