Abstract

AbstractA convenient procedure has been developed for the synthesis of C2‐symmetrical cyclic dinucleotide analogues that contain all‐pyrimidine bases (cytosine, uracil and thymine) with amide bonds in place of natural phosphodiester linkages, starting from commercially available d‐glucose diacetonide (GDA). The Vorbrüggen glycosylation of a common intermediate by using various pyrimidine bases was employed as the key step in the synthesis.

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