Abstract
A general synthesis of new alkyl 4-alkyl-2-hydroxy-3-oxo-3,4-dihydro-2 H-1,4-benzoxazine-2-carboxylate peptidomimetic building blocks from the corresponding alkyl 3-oxo-3,4-dihydro-2 H-1,4-benzoxazine-2-carboxylates through carbanion oxidation is described.
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