Abstract
Condensative cyclization of aldehydo-sugar S-methylhydrazonecarbodithioates and S-benzylhydrazonecarbodithioates with acetic anhydride in the presence of pyridine gave the corresponding 3-acetyl-2-(poly-O-acetyl-alditol-1-yl)-5-alkylthio-1,3,4-thiadiazolines. De-O-acetylation of the latter compounds gave the title acyclo C-nucleosides. The compounds prepared were found antimicrobially inactive against Escherichia coli, Bacillus subtilis, Staphylococcus aureus, and Candida albicans.
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