Synthesis of a pillar[5]arene-based [2]rotaxane with two equivalent stations via copper(I)-catalyzed alkyne-azide cycloaddition.

Abstract

A one-pot synthesis of pillar[5]arene-based [2]rotaxanes containing one and two stations by copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) reaction is reported. In situ formation of the two stations by two stepwise CuAAC reactions allows for the synthesis of a [2]rotaxane containing two stations with equal energy levels that exhibit shuttling of the pillar[5]arene wheel.