Synthesis of a new fluorescent poly(propylene imine) dendrimer modified with 4-nitrobenzofurazan. Sensor and antimicrobial activity

Abstract

In this work, we describe the modification of a poly(propylene imine) dendrimer with 4-chloro-7-nitrobenzofurazan performed for the first time. Its photophysical characteristics have been investigated in different organic solvents. The effect of the metal ions (Ag(I), Co(II), Sr(II), Pb(II), Mg(II), Cu(II), Fe(III) and Al(III)) upon its photophysical characteristics has also been studied. The new dendrimer enhances its fluorescence only in the presence of trivalent Al(III0 and Fe(III) ions. Also, the behaviour of the new compound in media of different pH has been investigated. The fluorescence intensity of the dendrimer in an acidic medium is about 22 folds higher than that in an alkaline medium. Antimicrobial tests indicated good antimicrobial activity of the synthesized compound against model strains Gram-positive and Gram-negative bacteria and yeasts. Antimicrobial activity of dendrimer has also been investigated upon its deposition onto a cotton fabric.