Abstract

Abstract Through a key step of regioselective rearrangement of 5′-O-acetyl-3,4′-O-isopropylidene-6-methylpyridoxine 1-oxide, stable 5′-deoxy-2′,5′-dichloro-3,4′-O-isopropylidene-6-methylpyridoxine hydrochloride, which is expected to be a strong electrophile in an HCl free form, was synthesized from Dl-alanine in good yield.

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