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Abstract
Δ 7-5-Desaturase catalyses one of the last steps in ergosterol biosynthesis in fungi. Moreover Δ 5-unsaturation is necessary for the sparking function. Synthesis of three pairs of C-6 epimeric cholestanol derivatives are described as potential growth inhibitors. Preliminary results suggest that 6β-aminocholestanol is a potent antifungal agent.
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