Abstract

An efficient method for the preparation of 6-methyltetrazolo[1,5-c]pyrimidin-5(6H)ones using as the precursors 4-chloro-1,2-dihydro-1-methyl-2-oxopyrimidines is described. The method is also extended to the synthesis of novel tetrazole analogue of 3′-azido-3′-deoxythymidine (AZT).

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