Abstract
A series of 2-aryl and 2-alkyl derivatives of 5-alkyl-4-oxazoleacetic acids was synthesized and tested for hypolipidemic activity. Among them, 5-isopropyl-2-(4-fluorophenyl)-4-oxazoleacetates exhibited potent activities, being more active than clofibrate [ethyl 2-(4-chlorophenoxy) isobutvrate].
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